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1) 신세포암 (Renal Cell Carcinoma) - 3% of adult cancer - 85... , 종 양사범교육레포트 ,
- 3% of adult cancer
- 85...
종 양
레포트/사범교육
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설명
,사범교육,레포트
순서
1) 신세포암 (Renal Cell Carcinoma)
- 3% of adult cancer
- 85% of all primary malignant tumor
- 40-50대에 흔히 발생, 남녀비는 2 대 1
(1) Etiology
① associated with von Hippel-Lindau disease, horseshoe kidney,
adult polycystic kidney disease, acquired renal cystic disease from CRF
② cigarette smoking - up to 30%
③ analgesic abuse - phenacetin
④ coffee, diuretics, obesity, estrogen
⑤ familial form - autosomal dominant
⑥ translocation of cellular oncogen:c-myc, c-ras
(2) Pathology
1> Origin: proximal renal tubular epithelium
2> Gross
- yellow to orange
- hemorrhage, necrosis, calcification
3> Micro
- clear cell, granular cell, mixed sarcomatoid cell
4> Pattern of progression
- direct inv…(省略)
1) 신세포암 (Renal Cell Carcinoma)
다.